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Ecies (32). Such enzymes could provide another means for Chl d biosynthesis. A. marina codes for 12 proteins with putative radical SAM motifs, far more than expected from an oxygen-producing cyanobacterium. Of these 12, two (AM1 5023 and AM1 5798) share very little homology with other sequenced cyanobacteria. The Chl d biosynthesis pathway may not be as simple as expected. Unlike the formyl side c
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Ecies (32). Such enzymes could provide another means for Chl d biosynthesis. A. marina codes for 12 proteins with putative radical SAM motifs, far more than expected from an oxygen-producing cyanobacterium. Of these 12, two (AM1 5023 and AM1 5798) share very little homology with other sequenced cyanobacteria. The Chl d biosynthesis pathway may not be as simple as expected. Unlike the formyl side c
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E the antibody isotype-profile of influenza-specific B cell responses. TLR7 plus type I IFN signaling can drive class switch recombination to IgG2a/c, while its stimulation without type I IFNR signaling drives IgG1 (75). This is consistent with studies showing that a lack of type I IFN direct signaling following influenza infection decreases IgG2a/c and increases IgG1 (30). Recently, TLR7 signalin
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Ed transposable regions for 20 of the genes, significantly lower than the 70 found in Nostoc sp. PCC7120 (2). This is partly because of the vast disparity in transposable elements in the two similarly sized genomes, with nearly 1,300 detected in Nostoc and only 500 in A. marina. Surprisingly, a large number of transposases and integrases in A. marina cluster together in regions with no detectabl
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Oteins including the plant and Prochlorococcus enzymes responsible for the synthesis of Chl b from chlorophyllide a, chlorophyllide a oxygenase (CAO) (Fig. 2) (31). Five putative proteins containing a CAO-type Rieske-FeS motif are encoded by A. marina. Most of the candidate genes in A. marina fall into orthologous clusters with other hypothetical cyanobacterial proteins (Fig. 2). Only one protein,
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Tegory (rings 1 and 2), deviation from average GC content (ring 3), and GC skew (ring 4). All plasmids are represented at 10 scale for visualization except pREB9 at 500. Color codes are as follows: turquoise, small-molecule biosynthesis; yellow, central or intermediary metabolism; orange, energy metabolism; red, signal transduction; light blue, DNA metabolism; blue, transcription; purple, protein
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Tegory (rings 1 and 2), deviation from average GC content (ring 3), and GC skew (ring 4). All plasmids are represented at 10 scale for visualization except pREB9 at 500. Color codes are as follows: turquoise, small-molecule biosynthesis; yellow, central or intermediary metabolism; orange, energy metabolism; red, signal transduction; light blue, DNA metabolism; blue, transcription; purple, protein
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Ed transposable regions for 20 of the genes, significantly lower than the 70 found in Nostoc sp. PCC7120 (2). This is partly because of the vast disparity in transposable elements in the two similarly sized genomes, with nearly 1,300 detected in Nostoc and only 500 in A. marina. Surprisingly, a large number of transposases and integrases in A. marina cluster together in regions with no detectabl