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Cullin-based E3 ligases. (A) Model of the ubiquitin proteasome pathway and (B-E) the four cullin-based E3 ligases found within plants. (B) SCF E3 ligases are composed of SKP1-like protein and an F-box containing protein that work together to bind to the CUL1 protein as well as facilitate targeting of specific substrates. Additionally (C) CRL3 and (D) CRL4 complex utilize variety of adapter protein
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Cullin-based E3 ligases. (A) Model of the ubiquitin proteasome pathway and (B-E) the four cullin-based E3 ligases found within plants. (B) SCF E3 ligases are composed of SKP1-like protein and an F-box containing protein that work together to bind to the CUL1 protein as well as facilitate targeting of specific substrates. Additionally (C) CRL3 and (D) CRL4 complex utilize variety of adapter protein
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Cullin-based E3 ligases. (A) Model of the ubiquitin proteasome pathway and (B-E) the four cullin-based E3 ligases found within plants. (B) SCF E3 ligases are composed of SKP1-like protein and an F-box containing protein that work together to bind to the CUL1 protein as well as facilitate targeting of specific substrates. Additionally (C) CRL3 and (D) CRL4 complex utilize variety of adapter protein
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To the AP3 promoter (Chae et al., 2008). LFY is also a target of SCFUFO dependent ubiquitylation, and although proteasomal activity is required for full expression of AP3, it remains open whether LFY is the primary target of SCFUFO activities(Chae et al., 2008). Since LFY is a positive modulator of AP3 expression it appears to be likely that repressors of AP3 expression are targeted first by SCFUF
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Chwieters, C.d., Shapiro, B.A., and Wang, Y.X. (2010). Solution structure of the cap-independent translational enhancer and ribosome-binding element in the 3' UTR of turnip crinkle virus. Proc. Natl. Acad. Sci. U S A 107: 1385-1390.The Arabidopsis Book?2014 American Society of Plant BiologistsFirst published on November 17, 2014: e0175. doi: 10.1199/tab.Composition, Roles, and Regulation of
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Chwieters, C.d., Shapiro, B.A., and Wang, Y.X. (2010). Solution structure of the cap-independent translational enhancer and ribosome-binding element in the 3' UTR of turnip crinkle virus. Proc. Natl. Acad. Sci. U S A 107: 1385-1390.The Arabidopsis Book?2014 American Society of Plant BiologistsFirst published on November 17, 2014: e0175. doi: 10.1199/tab.Composition, Roles, and Regulation of
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Nt F-box proteins, while others, like ASK4, ASK5, and ASK6, showed interactions with less than five (Kuroda et al., 2012). This may be indicative of a situation where only a subset of ASK proteins significantly participate in SCF activities. Also of interest is the large number of F-box proteins, 201 in total, that did not interact with any ASK proteins in these studies, suggesting that secondary
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Nt F-box proteins, while others, like ASK4, ASK5, and ASK6, showed interactions with less than five (Kuroda et al., 2012). This may be indicative of a situation where only a subset of ASK proteins significantly participate in SCF activities. Also of interest is the large number of F-box proteins, 201 in total, that did not interact with any ASK proteins in these studies, suggesting that secondary